Additionally, hnRNPK is involved in G6PD pre-mRNA splicing. PTEN and Tcl1 oppositely regulate the pentose phosphate pathway ... In order to examine whether Tcl1 represented a substrate of GSK3β, in ...

As a result, these in-vitro models provide only limited insights into how learning occurs in living systems. What if, however, we could create in-vitro neurons that more closely replicate natural ...

In vitro sensing using Escherichia coli produced GFP over a wide dynamic range ... In addition, fluorescence provides a direct link to protein-splicing activity. Thus, fluorescence-based biosensors ...

This manuscript describes the identification and characterization of 12 specific phosphomimetic mutations in the recombinant full-length human tau protein that trigger tau to form fibrils. This ...

Insilico Medicine ('Insilico'), a clinical-stage generative artificial intelligence (AI)-driven drug discovery and development company, today announced the nomination of ISM1745, a potentially best-in ...

Scientists have visualized the detailed structure of protein clumps linked to Huntington's disease, offering critical ...

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Oct. 18, 2024 — Researchers have developed an in vitro cancer model to investigate why breast cancer spreads to bone. Their findings hold promise for advancing the development of preclinical ...