As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

Activation of hepatic stellate cells is the central event in hepatic fibrosis. These perisinusoidal cells orchestrate an array of changes including degradation of the normal ECM of liver ...

The activation of hepatic stellate cells (HSCs) is involved in hepatoma progression, and accumulating evidence demonstrates a change in microRNA (miRNA) expression during HSC activation. Therefore, ...

az.vub.ac.be Accumulating evidence suggests that stellate cells are involved in the regulation of the liver microcirculation and portal hypertension. Activated hepatic stellate cells have the ...

1 Shandong University of Traditional Chinese Medicine, Jinan, China 2 Liuzhou People's Hospital Affiliated to Guangxi Medical University, Liuzhou, China Background: The etiopathogenesis of hepatic ...

Chronic liver damage can lead to hepatitis, which causes fibrosis of the liver. This buildup of collagen and other fibrous ...

Chronic liver damage can lead to hepatitis, which causes fibrosis of the liver. This buildup of collagen and other fibrous ...

A recent review published in eGastroenterology discusses recent advancements in understanding alcohol-associated liver ...

When TGF-β is converted from its biologically inactive form (LTGF-β) to its active form (TGF-β), it promotes fibrosis by activating hepatic stellate cells (HSCs). These cells transform into ...

Chronic liver damage can lead to hepatitis, which causes fibrosis of the liver. This buildup of collagen and other fibrous tissue accelerates when hepatic stellate cells become activated during ...

A newly published review in eGastroenterology compiles recent research on alcohol-associated liver disease (ALD), offering an ...

A recent report in Gastrointestinal and Liver Physiology presents the effect of a functional food called active hexose correlated compound (AHCC) on liver fibrosis. A Japanese firm, Amino Up Co.