As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

Activation of hepatic stellate cells is the central event in hepatic fibrosis. These perisinusoidal cells orchestrate an array of changes including degradation of the normal ECM of liver ...

肝脏是人体再生能力最强的实体器官。然而，持续的慢性肝损伤会显著抑制肝脏再生能力，进而导致肝纤维化的发生。肝星状细胞（Hepatic stellate ...

Microbial Cell Factories May Help Get to the Root of Understudied Plant Molecules Jan. 16, 2025 — A new tool could make it easier to study scarce plant molecules. Researchers have developed so ...

MASH is a consequence ... July 10, 2024 — In chronic hepatitis B, the liver contains immune cells that could destroy hepatitis B virus infected cells but are inactive. Researchers have ...

When liver function is impaired, the nitrogen-containing compounds begin to gradually build up, which causes an increase in ammonia levels. These ammonia particles then spread throughout the ...

Cell biology is the discipline of biological sciences that studies the structure, physiology, growth, reproduction and death of cells. Research in cell biology uses microscopic and molecular tools ...

The presence of two types of hair cells, the inner and outer hair cells, in the organ of Corti was appreciated nearly a 100 years ago but the function of the two has only become clear in the last 20 ...

The American Cancer Society’s estimates for primary liver cancer and intrahepatic bile duct cancer in the United States for 2025 are: About 42,240 new cases (28,220 in men and 14,020 in women) will be ...

Mesenchymal stem cells are multipotent adult stem cells that are present in multiple tissues, including umbilical cord, bone marrow and fat tissue. Mesenchymal stem cells can self-renew by ...

Liver needs to be very fresh; look for firm, proud, glistening livers with a deep pink-red colour. Most calves’ livers sold in the UK come from Dutch veal calves. If animal welfare is a concern ...

Hepatitis and cirrhosis are both diseases that affect the liver. Since hepatitis and cirrhosis are in many ways on a continuum of disease, the symptoms may be very similar. However, there are a ...