and five controls were used for absolute quantification of MUC2, assessment of sentinel goblet cell numbers and of goblet cell secretory responses to microbial challenge (online supplementary table S3 ...

Tiotropium had no effects on epithelial cell differentiation after air exposure. Differentiation into goblet cells was barely induced after air exposure. Therefore, IL-13 (1 ng/mL) was used to induce ...

a preliminary investigation was made of the histology and histochemistry of the gas gland to identify the types of cells which are involved in the secretion of gases.

Jan. 15, 2025 — While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows.

Dec. 23, 2024 — A research team has developed a groundbreaking technology that can treat colon cancer by converting cancer cells into a state resembling normal colon cells without killing them ...

Through simulation analysis, the team systematically identified master molecular switches that induce normal cell differentiation. When these switches were applied to colon cancer cells ...

unless a family history of early colon cancer is present. Colorectal cancer originates from epithelial cells lining the gastrointestinal tract, which undergo sequential mutations in specific DNA ...

Additionally, Alcian blue (AB) staining was employed to examine alterations in the mucous layer secreted by goblet cells within the colon. The colonic mucous layer serves as an effective ... Following ...

These regulators are known as MYB, HDAC2, and FOXA2 and when they were suppressed in colon cancer cells, the cells switched back to a normal-like state, removing the cancer threat without ...

In a trailblazing advancement in cancer therapy, researchers at Korea Advanced Institute of Science and Technology (KAIST) have developed a technology that transforms colon cancer cells into ...

"The results presented here show that an integrated approach addressing the challenges of uptake measurements enables the quantification of endocytosis in living cells. With quantitative ...