Our gut is a bustling hub of activity, home to trillions of microbes that work together with our bodies to keep us healthy. A recent study explores one fascinating aspect of this partnership: how gut ...
Major Finding: Elevated bile acids (BA) in liver cancer contribute to T-cell dysfunction. Concept: BA accumulation in T cells promotes ER stress, reducing effector function and viability. Impact: ...
The European Commission revoked the conditional marketing authorisation for Ocaliva (obeticholic acid) earlier this year ... allowing the FXR agonist to remain on sale, but the company confirmed ...
said that Ocaliva is the only FXR agonist for patients with PBC, and until now the only approved and available second-line treatment option in Europe after ursodeoxycholic acid (UDCA). Advanz ...
Hydrolases are enzymes that catalyze the cleavage of a covalent bond using water. Types of hydrolase include esterases, such as phosphatases, that act on ester bonds, and proteases or peptidases ...
Lean proteins such as chicken or fish, cooked vegetables, and whole grains are great GERD staples. Low-acid fruits, herbal teas, and plenty of water can also support digestion and soothe symptoms.