AbbVie has returned to the source of its antipsychotic powerhouse Vraylar in search of another blockbuster, paying $25 ...

An experimental first-in-class oral selective partial D1/D5 dopamine receptor agonist for Parkinson's significantly reduce ...

The molecules developed by companies in Pre-Registration, Filing rejected/ Withdrawn, Phase III, Phase II, Phase I, IND/ CTA Filed, Preclinical, and Discovery stages are 3, 2, 8, 12, 12, 1, 8, and 3 ...

Cells that use dopamine receptors for signaling may have one or more types of receptors ... Restless legs syndrome can be treated with levodopa, alpha-2-delta ligands (for example gabapentin), ...

Bromocriptine is unique in that it does not have a specific receptor that mediates its action on glucose and lipid metabolism. Rather, its effects are mediated via resetting of dopaminergic and ...

Fuchsberger et al. found that this strengthening of synaptic connections was mediated by two dopamine receptors (D1 and D5) that trigger a cascade of signals inside neurons. This includes activating ...

Caffeine's stimulating effects can paradoxically lead to sleepiness due to tolerance, adenosine receptor changes, and individual metabolic differences.

A "no internet" diet could benefit more than just the dopamine receptors. Australian scientists have suggested that internet ...

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