Cells use repair systems to fix this damage, with specialized proteins locating and binding to the damaged regions. Zooming in on individual cells The body has various mechanisms to repair DNA ...

Advance in stem cell therapy: New technique for manipulating stem cells opens door to novel treatments Aug 13, 2024 Scientists identify how a biological pathway leads stem cells to die or regenerate ...

By inhibiting the DNA polymerases, BKC enhances the endogenous RS in cancer cells, leading to increased DNA damage. IBC specifically inhibits CHK2 to prevent DNA repair. The combined use of BKC and ...

Northwestern Medicine investigators have discovered new molecular mechanisms underlying DNA repair dysregulation in prostate cancer cells, findings that may inform the development of new targeted ...

These could include strategies to counteract oxidative stress, enhance DNA repair or even remove damaged cells before they cause harm," Skowronska-Krawczyk said. "We plan to investigate which cell ...

In old cells with enlarged nucleolus, however, DNA repair is inaccurate leading to ... plan to study nucleolar effects on aging in human stem cells. Stem cells are special because they have ...

This triple-layered technique allowed the researchers to simultaneously capture the location of DNA, RNA and specific proteins in 3D space within individual mouse embryonic stem cells. With that ...

If cells are removed from the embryo they will differentiate into any cell type. These are called embryonic stem cells. Some stem cells remain in the bodies of adults as adult stem cells.

Hallmarks of aging, such as telomere attrition, genomic instability, and epigenetic changes, contribute to stem cell dysfunction. Furthermore, alterations in deoxyribonucleic acid (DNA ...

Neural stem cells: Crucial for brain development and repair, these cells also retain ... Prolonged exposure to space ...