Recently, type I interferons (IFNs), particularly IFNα and IFNβ, and their signalling pathways have been implicated in the pathogenesis of SLE, and these cytokines play an important role in lupus.
University of Michigan Medical School, Ann Arbor, Mich. Figure 1 summarizes the cells and cytokine pathways involved in pulmonary innate immunity against bacterial pathogens of the lung.
Figure 1. Cytokines in the TME of NPC. In the TME of NPC, increased levels of various cytokines are detectable. The EBV-infected cell product, LMP-1, upregulates CCL3, CCL4, IL-1β, and IL-8 expression ...