25, 2024 — Chromosomal instability plays a crucial role in the progression of cancer: it shapes the properties of tumor cells and drives the development of therapy resistance. Scientists used ...

The microbiome shapes the development of insulin-producing cells in infancy, leading to long-term changes in metabolism and ...

eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that ...

B cell and IL1β + monocyte/macrophage features associated with response to PD-1 blockade in cHL.

The discovery that a wide range of nano- and microparticles share the capacity to induce IL-1β secretion via activation of the NLRP3 inflammasome in dendritic cells and macrophages has led to the ...

Acanthocyte Erythrocyte identified by numerous spiny cytoplasmic projections; similar to a Burr cell Acanthocytosis ... which RBCs display both sizes and shapes that are variable and abnormal ...

Based on new brain mapping research funded by the National Institutes of Health (NIH), scientists have discovered that not all cell types in the brain age in the same way. They found that some ...

Nanoparticles (NPs) are versatile tools in various applications, particularly in the biomedical fields. To understand their behavior within biological systems, it is crucial to measure their ...

This important work substantially advances our understanding of reactive oxygen species (ROS) as a regenerative signal during postnatal cerebellum repair by activating adaptive progenitor ...

Recent advances in glial cell biology have unveiled their heterogeneity and crucial functions in modulating neural activity. Accumulating evidence indicates ...

Table 2. Distinction between atypical lymphoid proliferations rich in Reed–Sternberg-like cells (reactive immunoblasts) and classic Hodgkin lymphomas. Aspects Atypical lymphoid proliferations ...