Reporting in Nature Biotechnology ... inhibited the growth of subcutaneous B16 and K1735 melanoma cells and CT26 colon carcinoma cells to a greater extent, and induced tumour regression in ...

In immunocompetent mice injected with CT26 HER2 + tumor cells, CAR-M shrank HER2+ tumors with a 75% complete response rate and also showed activity against a contralateral HER2- tumor, indicating ...