The new year brought a few new laws to the D.C. area. Although July 1 and Oct. 1 are generally the big dates for new laws going into effect, here are a few you'll want to know about, whether you ...
Paraquat (1,1’-dimethyl-4,4’-bipyridyl dichloride) is a non-selective herbicide still widely used in agricultural crops in vast regions around the world for weed control (Zobiole et al. 2018) and also ...
The Young and the Restless spoilers reveal there is no new episode on Wednesday, January 1. So, what’s happening on Thursday, January 2, 2025? Fans will see Mariah Copeland (Camryn Grimes) react to ...
“I went from thinking everything was going to be fine to more than likely I'll be dead in the next five years," says Joshua Ray Walker of his up-and-down cancer battle in 2024. He's photographed ...
The Trump family Christmas card is making its way onto social media as grateful MAGA recipients are gleefully sharing images of the holiday greeting. The bright red card features a gold star with ...
The shocking full list of demands Blake Lively made for Justin Baldoni and others on the set of It Ends With Us has been revealed. The pair starred alongside each other in the film adaptation of ...
S1P, through SphK2, affects the expression levels of PPARγ and its downstream protein CD36, improving sugar and lipid metabolism as well as insulin resistance. Moreover, S1P activates PP2A to inhibit ...
This landmark study elucidates the intricate structural mechanisms by which both covalent and non-covalent synthetic ligands can co-occupy the binding pocket of the nuclear receptor transcription ...
Crystal structures of PPARγ LBD in the transcriptionally active and repressive conformations. The active LBD (PDB 6ONJ) is stabilized by agonist (rosiglitazone) and coactivator peptide (TRAP220/MED1), ...