Relatively unknown brain cells—"astrocytes"—are believed to play an important role. At the Uppsala Biomedical Center, lab researchers are attempting to learn more about their function in order ...

The collected cells were analyzed by single cell reverse transcription quantitative polymerase chain reaction (scRT-qPCR), to identify changes in the expression of genes that encode membrane proteins ...

The potential effects of astrocyte dysfunction in neurodegenerative ... been hypothesized to result from the failure of astrocytic functions that require cell–cell coupling to maintain their ...

Fingolimod treatment leads to beneficial effects in Huntington disease (HD), according to a new study in a mouse model of the ...

State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China University of Chinese Academy of ...

There is no doubt about the importance of astrocytes in maintaining CNS health, while their role in CNS disorders seems to be ambiguous. The failure of their crucial functions has emerged to be one of ...

In a 2017 study, researchers in China showed that when astrocyte function is compromised, animal models tended to develop depression-like symptoms. Vijayaraghavan and Andrew Novick, MD ...

Here we show depletion of mitochondrial DNA and decrease in mitochondrial activities result in neuronal differentiation defects. Increased astrocytes, which are secondary responders to ...

Christopher H. Contag and Ahmed A. Zarea explore therapeutic approaches to neurodegenerative diseases using a novel strategy ...