LIN can improve the cachexia symptoms of DDP-treated tumour-bearing mice and reduce muscle atrophy without affecting the anti-tumor efficacy of DDP. The mechanism is that LIN can down-regulate the ...
In amongst a clutch of discontinued phase 3 programmes in Roche's fourth-quarter results update was the news that it has stopped a study of AKT inhibitor ipatasertib as a treatment for first-line ...
In mathematics, a bearing is the angle in degrees measured clockwise from north. Bearings are usually given as a three-figure bearing. For example, 30° clockwise from north is usually written as ...
Dual blocking SHP2 and FGFR2 can not only promote the targeted tumor-killing effects and overcome FGFR2 inhibitor resistance caused by feedback activation, but also activate T cell-mediated anti-tumor ...
Clinical and Radiographic Outcomes of Four Different Treatment Strategies in Patients With Early Rheumatoid Arthritis (the Best Study): A Randomized, Controlled Trialfrom Arthritis & Rheumatism ...
i.e., with patients fully bearing the cost, the drug price for the overall population group needs to be reduced to $33.66/200 mg to $38.39/200 mg, with a maximum reduction of up to 91.1%, to be ...