A research team led by Prof. Feng Wei at the Institute of Biophysics, Chinese Academy of Sciences, has made significant ...

Lysosomes, often reductively referred to as the "garbage disposals" of cells, play a pivotal role in our cells' digestive systems by getting rid of unwanted materials.

The biotech is focusing on precision, small-molecule medicines that work via a process known as cellular clearance by activating the lysosome, sometimes referred to as the cell’s recycling and ...

When STING is triggered, TANK-binding kinase (TBK1) activates and leads to interferon production. However, Tan and his team ...

The Lysosome This small particle acts as the digestive tract of the living cell. Its enzymes dissolve the substances ingested by the cell and under certain circumstances can dissolve the cell itself ...

Microglia can partially break down amyloid plaques by "spitting" a digestive enzyme at them, a new study has found.

Early work revealed that TFEB is highly effective in ameliorating tau/NFT pathology and rescuing cognitive impairment and neurodegeneration. TFEB targets only the aberrant tau species and this ...

Immune cells in the brain called microglia can partially break down large amyloid plaques characteristic of Alzheimer's disease by latching on to ...

The lab also studies mechanisms that regulate autophagy protein and lysosome function in endocytic trafficking and nutrient homeostasis. Figure 1. Entosis promotes cell competition. (A) Entosis ...

The lab also studies mechanisms that regulate autophagy protein and lysosome function in endocytic trafficking and nutrient homeostasis. Cell biologist Michael Overholtzer explores genes that make ...