Study Links Genomic Instability to Aggressive Bone Cancer
A study identified the mutation mechanism LTA chromothripsis in 50% of high-grade osteosarcoma cases, explaining its genomic ...
The EMBO Journal12d
The dynamics of loss of heterozygosity events in genomes
This month's cover highlights the article A novel bacterial effector protein mediates ER-LD membrane contacts to regulate ...
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Genetic variation enhances cancer drug sensitivity in specific patient groups, study shows
The human genome is organized into 46 chromosomes, where all but the X and Y chromosomes in men are present in two copies. This means that a person with a faulty gene on one chromosome most often ...