Fortunately, the high functional specialization of cDC1s means that few of these cells are required to be present in tumors—approximately 0.1%—to achieve effective anticancer immunity.

We have recently addressed this question (Antonelli et al) using the MB49 mouse model. We demonstrated that BCG induces tumor specific T cell immunity which is largely dependent of tumor specific CD4 ...

The immune system plays a pivotal role in colorectal cancer (CRC), with immune cells such as T cells, natural killer (NK) cells, macrophages, and dendritic ...

Heritage hospital Gorakhpur Novo Nordisk acquires Corvidia Scientists discover dangerous T cells in pancreatic tissue New trends in lung cancer tumor immunity: Can drug O regain growth after drug K’s ...

Researchers at Emory Universitys Winship Cancer Institute discovered a new form of immune cell known as the stem-like CD4 T ...

A new generation of cancer therapies has emerged over the past few decades, including checkpoint inhibitors and chimeric antigen receptor (CAR) T-cell therapies that modify or directly use T-cells ...

Although targeting Tregs to restore anti-tumor immunity is an emerging area in cancer therapy, systemically inhibiting Tregs ...

A new publication from Genes & Diseases; DOI  10.1016/j.gendis.2024.101441, discusses how Ce6-GFFY is a novel photosensitizer ...

Furthermore, the researchers showed that chronic activation of these immune pathways can contribute to tumor development in a ...

These axes of regulation are crucially important in shaping the immune system when it is activating in metabolically demanding environments, such as tumor tissue. Indeed, the immune response to cancer ...