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2 天
《科学》子刊:一键“改邪归正”!复旦团队找到激活肿瘤相关巨噬 ...
*仅供医学专业人士阅读参考让肿瘤微环境里一些走上邪路的细胞“浪子回头”,从抑制抗肿瘤免疫应答变为助力免疫应答,应该算是许多科研工作者的夙愿了,而常被提到的挽救对象之一就是肿瘤相关巨噬细胞(TAMs),不过让它们改邪归正的难度确实不小,奇点糕也经常在想 ...
News Medical on MSN
17 小时
P-stalk ribosomes identified as key regulators of immune evasion in cancer
Research uncovers how P-stalk ribosomes regulate cytokine responses, driving immune evasion in tumors across multiple cancer ...
GEN
5 天
Cancer Research Institute Awards Honor Contributions to T-Cell Research and Autoimmune ...
The awards celebrate the discovery of a new role for CD4 T cells in the cancer immune response and insights into autoimmune ...
technologynetworks
22 小时
How Gut “Surveillance” Cells Detect Harmful Invaders
These cells, located in parts of the gut like the ileum, can activate CD8+ T cells, which are key players in the immune ...
腾讯网
6 天
Cancer Cell | 钱丹雯等绘制肿瘤内B细胞的单细胞RNA测序全景图谱
引言肿瘤免疫微环境对癌症的发生、预后及治疗的贡献已广为认可,尤其是在固有免疫因素和T细胞亚群的研究方面。然而,尽管有证据表明肿瘤浸润B细胞在多种癌症中占据显著比例,甚至在某些情况下占所有肿瘤浸润淋巴细胞的40%,但肿瘤免疫微环境中B细胞的研究相对较少 ...
2 小时
800% Upside For This Biotech Stock - Analyst Initiates Coverage On Bladder Cancer Focused ...
EF Hutton has initiated coverage on ImmunityBio Inc. (NASDAQ:IBRX), a vertically integrated biotechnology company developing ...
studyfinds
9 天
Chronic stress linked to worsening cases of colorectal cancer
In an alarming discovery, researchers have uncovered a startling link between chronic stress and the progression of ...
生物谷
12 天
西湖大学高晓飞团队开发红细胞-MHC-I偶联药物,用于癌症治疗
之前已有研究探索了多肽-MHC融合蛋白与其他分子在红细胞中调控免疫反应以治疗癌症的作用,而仅含有MHC-I分子的红细胞在免疫激活方面的有效性仍有待研究。 2023年9月,高晓飞团队在 Cell Research ...
腾讯网
1 小时
Nat Cell Biol | Cdk5调控乳腺癌脑转移
引言脑转移(BrM)是一种癌细胞从身体其他部位转移到大脑的现象,原发性癌症转移至大脑的最常见类型是肺癌、乳腺癌等,BrM可能发生在原发性癌症治疗后数月甚至数年,BrM患者的生存期较短。到目前为止,BrM的免疫逃避机制仍不清楚。近日,来自美国德克萨斯大 ...
13 天
on MSN
Disrupting Asxl1 gene prevents T-cell exhaustion to improve immunotherapy, researchers discover
Immunotherapy, using a patient's own immune system to treat disease, has shown promise in some patients with cancer but has ...
News Medical
11 天
Gene editing enhances immunotherapy success by preventing T-cell exhaustion
Immunotherapy, using a patient's own immune system to treat disease, has shown promise in some patients with cancer but has ...
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