Sethi emphasized the need for studies like this one that shed light on the molecular details of how serrated adenomas form and progress ... deletion of one or both aPKC in intestinal epithelial cells, ...

Conventional adenomas were thought to develop from mutations in the normal stem cells that lie at the bottoms of intestinal crypts, pit-like structures in the lining of the intestine. Serrated ...

The studies were carried out in genetically modified mice and intestinal organoids from mice and humans—self-organized three-dimensional tissues derived from stem cells in the intestine.

A team of Korean researchers succeeded in mass cultivating human intestinal stem cells in an environment without any animal-derived components for the first time in the world, paving the way for ...