Surprisingly, it does this in the absence of both messenger RNA and the ribosome’s small, message-reading subunit. The ribosome is a large molecular complex of RNA and protein. When eukaryotic ...

Then the SRP–signal peptide–ribosome complex binds to the ER membrane via an SRP receptor. The signal peptide is then inserted into the ER membrane via a signal peptide binding protein and the ...

Ribosomal translation is the process by which cells synthesize proteins based on the genetic instructions encoded in messenger RNA. It is essential for life, yet it is an incredibly complex process ...

We showed that non-AUG translation is strikingly resistant to multiple protein synthesis inhibitors, including cycloheximide. We find that these inhibitors slow elongating ribosomes, thereby inducing ...

These rRNAs play a role in peptide bond formation and translocation. The rRNA molecules fold into complex secondary and tertiary structures, forming domains and motifs that are essential for ribosome ...

Researchers at the University of Hawaiʻi at Mānoa have made an exciting discovery : a virus found in the ocean called ...

Previous research in yeast showed that when translation slows down, only one tRNA is left in the ribosome, in the P site. When the A and E sites are empty for a long time, a complex called CCR4 ...

In cells, ribosomes (shown as grey blobs ... on material and machinery provided by the host cell, but larger, more complex viruses code for numerous proteins to aid in their own replication.

Transmission electron micrograph of negatively stained FloV-SA2 virus particles (top left). Scale bar: 100 nm; A ribosome ...