How does DNA recombination work? It occurs frequently in many different cell types, and it has important implications for genomic integrity, evolution, and human disease. In the alternate pathway ...

You have full access to this article via your institution. To demonstrate the power of PCR–mediated recombination and provide an example of the general utility of the method, we constructed ...

We are studying the mechanism and regulation of meiotic recombination in mouse. Portions of this work are part of a longstanding collaboration with Maria Jasin’s lab in the Developmental Biology ...

Homologous recombination plays essential roles in the repair of DNA double strand breaks (DSBs) and collapsed replication forks. The fundamental reaction in homologous recombination is the exchange of ...

When DNA damaged by radiation was repaired by a method called homologous recombination, they found that cancer cells died during reproduction, a process called cell division or mitosis.

Sydney: Australian researchers have found that DNA repair may determine how cancer cells die following radiotherapy in a new ...

Published in Clinical Cancer Research, results of a VHIO-led study underscore the potential of the RAD51 biomarker in ...

Recombination is a process by which pieces of DNA are broken and put back together to produce new combinations, which creates ...

How do tumor cells die after radiotherapy- one of the most important type of cancer treatment- is one of the big mystery in ...

Colloidal quantum dots (QDs) constitute a platform to explore various quantum effects. Their size-dependent colors are ...

Developed in-house by Serra’s laboratory, a test based on the detection of the RAD51 protein as a functional biomarker of ...

MOMA Therapeutics on Wednesday said it added the next-generation PARP1 inhibitor MOMA-989 to its pipeline of drug candidates and anticipates filing an investigational new drug application by year end ...