and RNA-induced silencing complex (RISC) complex. Sixfold applied this to the extracellular space, hypothesizing that modifications are dictating the delivery mechanism and destination by altering ...

Furthermore, many other varieties of RNA have been found to have complex regulatory roles in cells. Thus, RNA molecules play numerous roles in both normal cellular processes and disease states.

This valuable study addresses potential roles of the master regulator of X chromosome inactivation, the Xist long non-coding RNA, in autosomal gene regulation. Using data from mouse cells, the authors ...

Sometimes, words are not all they are cracked up to be. Silence can yield more power than words. Inventor and artist Leonardo da Vinci said, “Nothing strengthens authority so much as silence.” ...

Overview of RNA repair – There is an emerging appreciation of the existence of “RNA repair ... We recently solved a 2.2 Å crystal structure of the Candida Trl1 kinase domain in complex with GDP and Mg ...

TIME’s editor-in-chief on why the Silence Breakers are the Person of the Year It became a hashtag, a movement, a reckoning. But it began, as great social change nearly always does, with ...

The study is a valuable addition to the field, showing how particulate matter may be acting via nociceptor neurons towards neutrophilic asthma exacerbations. The solid evidence for the role of a ...

At 11am on each Remembrance Sunday a two minute silence is observed at war memorials and other public spaces across the UK. The silence is meant as a tribute to those who lost their lives fighting ...

Drug-induced lupus is more common in men because they are given these drugs more often; however, not everyone who takes these drugs will develop the disease. Specific criteria for diagnosing ...

One of the main challenges is understanding the complex interplay between guanine and the other nucleobases in the context of DNA and RNA structure and function. Investigating how modifications to ...

The experience of grappling with hearing issues is a unique and often challenging journey that can impact various aspects of one’s life. What may start as a minor inconvenience can escalate into ...

There are three types of sentence - simple, compound and complex. All three have an equally important role in writing. Complex sentences can be useful for presenting ideas that need layers of ...