When a gene produces too much protein, it can have devastating consequences on brain development and function. Patients with an overproduction of protein from the chromodomain helicase DNA binding ...

In patients with this rare disorder, a long non-coding RNA called CHASERR (CHD2 adjacent ... then they can perform genome ...

RNA editing has picked up steam in recent years as a potentially safer alternative to gene editing to treat genetic diseases.

In patients with this rare disorder, a long non-coding RNA called CHASERR (CHD2 adjacent ... then they can perform genome ...

Long non-coding RNAs represent a paradigm shift over the last two decades, as better scientific understanding of their ...

Xu Jianguo, an academician of the Chinese Academy of Engineering, said that the success of LucaProt marks a breakthrough for ...

Early data from Wave Life Sciences suggests how editing RNA may yield viable medicines. Large and small drugmakers say such ...

Scientists at Colossal Biosciences may be a few steps closer to resurrecting a long-extinct carnivorous marsupial known as ...

10 月 7 日，瑞典卡罗琳斯卡医学院宣布，2024 年诺贝尔生理学或医学奖授予美国科学家 Victor Ambros 和 Gary Ruvkun 以表彰他们发现了 microRNA (miRNA，微小 RNA) 及其在基因调控中的作用。

A research team from the University of Barcelona's Institute of Neurosciences described a novel molecular mechanism that ...

This valuable study addresses potential roles of the master regulator of X chromosome inactivation, the Xist long non-coding RNA, in autosomal gene regulation. Using data from mouse cells, the authors ...

结论：这项研究揭示了在肿瘤中广泛积累的异常 miRNA 异构体，并开发了一种通过编辑和修复有缺陷的 miRNA 来实现的植物 RDR1 介导的抗肿瘤策略。这些发现为癌症治疗提供了新的视角，即通过利用植物免疫蛋白来修复肿瘤中的 miRNA 缺陷，从而抑制肿瘤生长。