Originally developed for psoriasis and gout but later discontinued, the purine nucleoside phosphorylase (PNP) inhibitor Ulodesine now shows promise as an immune checkpoint inhibitor to treat leukemia.

Sugars, purines and pyrimidines can be made in relatively ... We have therefore investigated certain aspects of prebiotic nucleoside synthesis.

Recently, we observed that acute pericarditis was produced in 3 of 4 patients given at least five days' treatment with psicofuranine, a new purine nucleoside analogue. 13 Pericarditis has also ...

Structural formula of inosine. Inosine is a nucleoside containing hypoxanthine and ribose. It differs from adenosine by the absence of an amino group at the 6 position of the purine ring. (Image: ...