Scientist Michel Brahic's new book delves into the world of prions, the culprits behind some of the scariest illnesses around ...

an animal disease linked to misfolded prion protein (PrP). In 2001, Soto's group described the development of the 'protein misfolding cyclical amplification' (PMCA) assay, in which brain tissue ...

Figure 1: QUIC reactions seeded with brain homogenates and CSF samples from normal or scrapie-affected hamsters. These observations suggest that a diagnostic test for prion infections based on CSF ...

"Scrapie" is the old Scottish shepherds' name for a disease of their sheep which has been known for several centuries. It is the original example of a group of diseases, known as the ...

Over time, this zombie-like accumulation of diseased prions destroys the brain from the inside out, though it can take years ...

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Discover the applications of Ttau PFFs and alpha-synuclein PFFs in advancing neurodegenerative disease research.

The clinical worsening after microglia envelop neurons suggests the phenomenon is harmful, the authors noted. “With disease progression, microglial behavior changes from positive to negative,” ...

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Heparin treatment was associated with a delayed diagnosis of Alzheimer's dementia, electronic health records in two U.S.

These prions cluster together, forming lengthy fibers that eventually turn into plaques, akin to the process by which amyloid-beta and tau proteins accumulate and expand in the brain in cases of ...

A handful of whitetails in the Illinois deer herd gather for an early November meal in a freshly-shelled field of corn. The ...