Isolated alcoholic binges rarely, if ever, cause pancreatitis. Pancreatic stellate cells have been identified as the key effector cells in the regulation of pancreatic fibrosis. Activation of ...

pancreatic stellate cell; Shh, sonic hedgehog; TME, tumor microenvironment. Another ECM-targeting strategy is pamrevlumab, a monoclonal antibody that inhibits the activity of connective tissue growth ...

The relationship the immune system and stromal cells in pancreatic cancer can have a significant impact on patients' survival rates, according to findings of a Queen Mary-led study. Pancreatic ...