One of the problems in determining PD-L1 expression is that it is dynamic; expression changes over time 6 and is influenced by cells, such as antigen-presenting cells — which also express PD-L1 ...

This study will focus on the treatment of newly diagnosed locally advanced primary head and neck cancer patients with no lymph node involvement and low (TPS <10) PD-L1 tumor expression.

In vitro PD-L1 targeted CAR-NK cells demonstrated specific anti-tumor activities against 15 tumor cell lines, and in vivo, they showed substantial anti-tumor effects against triple-negative breast ...