p53 is a common denominator among human cancers. How was it discovered? What are the persistent questions about its function? Aa Aa Aa It seems nearly impossible for a normal cell to become a ...

a group of researchers investigated the role of Fas Cell Surface Death Receptor (FAS) in regulating Tumor Protein p53 (p53) expression in adipocytes and its impact on energy metabolism ...

One helper in this process is the p53 protein. However, when it mutates, it can no longer fulfill its task. Until now, researchers have assumed that the process is the same with all mutation types.

The human body contains proteins that are designed to protect us from cancerous growths. Like most proteins, to do their job properly, these “guardians” have to fold into a specific three-dimensional ...