However, under the low stringency conditions required for short nucleic acid probes to form stable interaction, the longer single-stranded targets are able to engage in secondary structure.
Improve assay sensitivity and specificity with Locked Nucleic Acid oligonucleotides (LNA oligos ... Additional advantages: Access LNA probes for multiplexing with a full suite of fluorophores.
Enver Cagri Izgu, from the School of Arts and Sciences at Rutgers-New Brunswick, and his team will use a nearly $2 million ...
The miRCURY LNA Array system uses locked nucleic acid (LNA TM), a high-affinity nucleotide analog, to enhance the array capture probes, giving them high sensitivity and excellent selectivity for ...
It uses the fact that denatured nucleic acids will bind to nitrocellulose or nylon membranes ... This immobilizes the DNA fragments, allowing specific sequences to be identified by hybridization with ...
Optical tweezers offer high force and spatial resolution, making them suitable for studying the mechanical properties of nucleic acids, motor proteins, and protein-protein interactions ... By ...
DST said that the fluorogenic molecular probe (BBJL) developed by Sumon Pratihar ... of detection techniques targeting noncanonical nucleic acids,” it said. According to DST, the molecular ...