However, under the low stringency conditions required for short nucleic acid probes to form stable interaction, the longer single-stranded targets are able to engage in secondary structure.
Improve assay sensitivity and specificity with Locked Nucleic Acid oligonucleotides (LNA oligos ... Additional advantages: Access LNA probes for multiplexing with a full suite of fluorophores.
Nucleic acid medicine allows for rational drug design ... That’s allowed researchers to probe ways to adapt them and their properties to improve immunity. The dendritic cell bonanza has, in ...
It uses the fact that denatured nucleic acids will bind to nitrocellulose or nylon membranes ... This immobilizes the DNA fragments, allowing specific sequences to be identified by hybridization with ...
Optical tweezers offer high force and spatial resolution, making them suitable for studying the mechanical properties of nucleic acids, motor proteins, and protein-protein interactions ... By ...
DST said that the fluorogenic molecular probe (BBJL) developed by Sumon Pratihar ... of detection techniques targeting noncanonical nucleic acids,” it said. According to DST, the molecular ...