In the PNS, one Schwann cell forms a single myelin sheath (Figure 1A). By contrast, in the CNS, the oligodendrocyte sends cell processes to myelinate multiple segments on many axons (Figure 2).

Charcot-Marie-Tooth (CMT) disease, a group of heritable disorders that affect the peripheral nerves, is marked by specific genetic changes. Research by the team of Prof. Ludo Van Den Bosch (VIB-KU ...

They are often between the ages of 30 and 60. Acoustic neuroma tumors begin in what are called Schwann cells. These cells make myelin, which is the material that insulates and protects the nerves ...

Myelin – produced by Schwann cells in the periphery and oligodendrocytes in the CNS – is defective in diseases such as multiple sclerosis, and many myelin repair strategies aim to mitigate ...

In a test tube, AMPK activation reversed insulin resistance in Schwann cells, which form the myelin sheath that cover the nerves. "Taken together, these results help us understand how peripheral ...