但是,关于线粒体如何调控铁死亡的具体仍然未知。 近日,来自美国阿尔伯特-爱因斯坦医学院的Richard N. Kitsis在Molecular Cell上发表了论文OPA1 promotes ferroptosis by augmenting mitochondrial ROS and suppressing an integrated stress ...
Share on Pinterest Scientists have found that mitochondria may play a role in triggering Crohn’s disease. Hernandez & Sorokina/Stocksy As of 2019, about 4.9 million people globally were living ...
As an inhibitor of ATPase, Ru5 induces mitochondrial dysfunction, autophagy, and ferroptosis, which collectively contribute to its antitumor efficacy. Furthermore, comprehensive multi-omics ...
It is the mitochondrion, a small body which appears to play a central role in the oxidation of foodstuff. Its structure, as revealed by the electron microscope, mirrors its function ...
This new article publication from Acta Pharmaceutica Sinica B, discusses how heme oxygenase 1-mediated ferroptosis in Kupffer cells initiates liver injury during heat stroke. With the escalating ...
It offered promising results in activating parkin, a key protein in the brain responsible for tagging damaged proteins in mitochondria. Experts say the molecule’s ability to assist patients with ...
The Thompson laboratory has proposed that the basis of metazoan cell survival is determined by the inability of cells to take up nutrients in a cell-autonomous fashion. This hypothesis was formulated ...