引言近年来,免疫治疗作为治疗癌症、感染性疾病以及自身免疫疾病的一种新兴策略,展现了巨大的潜力。然而,其核心挑战在于如何实现对病变细胞的精准识别和杀伤。传统的免疫疗法多依赖于单一靶点,如肿瘤表面特异性抗原,但这种方法易导致靶点突变或逃逸,使治疗效果大打 ...
研究背景      主要组织相容性复合体(Major Histocompatibility Complex, ...
MHC tetramers are typically prepared with most of the commonly used fluorescent labels used for flow cytometry. One major advantage of the technique is that the label is already attached to the ...
T cells use the T cell antigen-receptor (TCR) to recognize their antigens, which are often in the form of peptides bound to major histocompatibility complex molecules (MHC), also called HLA (human ...
Viral protein is made intracellularly and the protein is processed via the endogenous MHC class I pathway. DNA vaccines. DNA vaccines favor a cell-mediated immune response. DNA plasmid vector ...