Alterations in metabolism, inflammation, fibrosis and cardiac cell death by apoptosis are some ... together with mitogen-activated protein kinase (MAPK) activity, induces cardiomyocyte cell ...

(IGF1, insulin-like growth factor 1; MAPKAP-K1, mitogen-activated protein kinase (MAPK)-activated protein ... GSK3 inhibitors have been shown to prevent the apoptosis of neuronal cells that ...

Aberrant activation of the Ras/Raf/MAPK/ERK kinase/extracellular signal ... cell growth, prevention of apoptosis, tumor invasion and neo-angiogenesis. Sorafenib is an oral multikinase inhibitor ...