Given the uncertainties of the pathogenesis of lupus nephritis, the need to correlate specific histologic findings with treatment and outcomes, and the need to identify biomarkers that accurately ...

Lupus nephritis (LN) is one of the most serious ... Results from these studies bring new insights for real effective treatment in LN and thus achieve a better outcome in patients.

Objective Both belimumab and telitacicept are recognised blockers for B lymphocyte activation, both of which have been ...

Although the unpurified extract is reportedly an effective treatment for lupus nephritis in mice, the effects of triptolide and tripdiolide, thought to be the two most therapeutically active ...

Caribou Biosciences has launched a Phase 1 trial testing its CAR T-cell therapy CB-010 for lupus affecting the kidneys and ...

The Phase 1 GALLOP study evaluating the investigational therapy, CB-010, for treatment of lupus nephritis has launched.

The Phase 1 GALLOP study evaluating investigational therapy, CB-010, for treatment of lupus nephritis (LN) has officially started. This open label, multicenter study will assess a single infusion of ...

Kyverna Therapeutics, Inc., a leading biotechnology company focusing on autoimmune diseases, revealed its strategic priorities for the year 2025 and anticipated milestones in a recent press release on ...

Zanubrutinib is under clinical development by BeiGene and currently in Phase II for Lupus Nephritis. According to GlobalData, Phase II drugs for Lupus Nephritis have a 50% phase transition success ...

Improvement in results on a noninvasive urinary biomarker panel at 3 months among patients with lupus nephritis predicted a clinical response at 1 year. A noninvasive urinary biomarker panel ...

CCAR-168 is under clinical development by AbelZeta and currently in Phase I for Lupus Nephritis. According to GlobalData, Phase I drugs for Lupus Nephritis have an 84% phase transition success rate ...

Lupus nephritis, or kidney involvement in lupus ... For severe cases or when organ systems are involved, treatment may include: Immunosuppressive drugs: Medications such as azathioprine ...