The discovery of the tyrosine kinase Syk, the development of powerful mouse models for pancreatic and colon cancer, and the mechanistic exploitation of the folate receptor, are examples of Purdue ...

All the ERBB receptors except ERBB2 have known ligands, and all except ERBB3 have relatively active kinase domains. Although ERBB2 is minimally active in ligand binding, it is the preferred ...