Notably, intracellular checkpoint molecules within NK cells, such as FBP-1, EZH2, CIS, TIPE2, and HIF-1α, play a significant role in NK cell exhaustion by affecting their metabolism ...
We aim to understand how nanoparticles deliver biological drugs inside cells, and use these understanding to develop new nanomedicine for novel biotherapeutics. Our research topics are at the ...
NK cells’ metabolism, proliferation, survival, and cytotoxic function are all impacted by intracellular checkpoint molecules such as FBP-1, EZH2, CIS, TIPE2, and HIF-1α, which significantly ...