But new “organs-on-chips” technology is emulating the liver, brain, lungs, intestines, and more on a chip the size of a USB stick. Until now scientists conducted most biomedical research ...

The Organ-Chip platform is particularly well ... to model the intestinal epithelial barrier (referred to as a “Caco-2 Intestine-Chip” in short). This innovative chip design enables the precise ...

The organ-on-a-chip is a recent outgrowth of this effort, comprising systems that extend beyond microfluidic perfusion culture to allow the establishment of microphysiological systems comprising ...

In our recent study, we developed a PBPK compliant ADME 4-Organ-Chip (Chip4) with a downscale factor of 1:100.000 of the human body. The integration of an intestinal barrier model for absorption and ...

Failure in late stages of the drug development pipeline is one of the major challenges that the pharmaceutical industry faces today. Human organ-on-a-chip (Organ-Chip) technology has the potential to ...