As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

It may soon be possible to determine which patients with a type of liver cancer called hepatocellular carcinoma would benefit ...

An “out-of-this-world” project has the potential to transform the future of tissue engineering and liver transplantation ...

Researchers at Weill Cornell Medicine have made a breakthrough in the fight against liver cancer, by identifying a biomarker ...

Biomarker NBR1 shows promise in predicting liver cancer patients' response to immunotherapy, potentially improving treatment ...

Microscopy image showing activated hepatic stellate cells (HSCs), indicated by red staining (left image). Inhibition of CYB1B1 reduces HSC activation (right image), which leads to reduced liver ...

It may soon be possible to determine which patients with a type of liver cancer called hepatocellular carcinoma would benefit from immunotherapy, according to a preclinical study by Weill Cornell ...

The final patient completing our pivotal F351 Phase 3 trial marks an important milestone for Gyre and our development pipeline. We are grateful to the patients, researchers, trial investigators, and ...

2017 Exosome mediated intercellular communication between hepatitis C virus infected hepatocytes and hepatic stellate cells. J Virol. 91(6). pii: e02225-16. PMCID: PMC28077652 Sasaki R, Devhare PB, ...

Activation of hepatic stellate cells is the central event in hepatic fibrosis. These perisinusoidal cells orchestrate an array of changes including degradation of the normal ECM of liver ...

According to a preclinical study conducted by Weill Cornell Medicine researchers, it may soon be feasible to detect whether ...

What are hepatic stellate cells (HSCs), and how do they contribute to liver fibrosis? HSCs are a unique cell type in the liver. When the liver is injured or inflamed, HSCs become activated and ...