As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

Abstract & Introduction Activated Hepatic Stellate Cells as a Target For Antifibrotic Therapy Current Therapeutic Approaches in Liver Fibrosis Concluding Remarks References Many treatments ...

Researchers at Weill Cornell Medicine have made a breakthrough in the fight against liver cancer, by identifying a biomarker ...

【导读】肝细胞癌(HCC)常发生在纤维化或肝硬化的背景下。组蛋白甲基化是一种重要的表观遗传机制，但目前尚不清楚组蛋白甲基转移酶是否为纤维化相关HCC治疗的有效靶点。10月8日，南方医科大学研究团队在期刊《Advanced ...

It may soon be possible to determine which patients with a type of liver cancer called hepatocellular carcinoma would benefit ...

近日，来自美国匹兹堡大学谢文教授团队在《科学转化医学》（Science Translational ...

According to a preclinical study conducted by Weill Cornell Medicine researchers, it may soon be feasible to detect whether ...

Biomarker NBR1 shows promise in predicting liver cancer patients' response to immunotherapy, potentially improving treatment ...

Microscopy image showing activated hepatic stellate cells (HSCs), indicated by red staining (left image). Inhibition of CYB1B1 reduces HSC activation (right image), which leads to reduced liver ...

What are hepatic stellate cells (HSCs), and how do they contribute to liver fibrosis? HSCs are a unique cell type in the liver. When the liver is injured or inflamed, HSCs become activated and ...

What are hepatic stellate cells (HSCs), and how do they contribute to liver fibrosis? HSCs are a unique cell type in the liver. When the liver is injured or inflamed, HSCs become activated and ...

The final patient completing our pivotal F351 Phase 3 trial marks an important milestone for Gyre and our development pipeline. We are grateful to the patients, researchers, trial investigators, and ...