As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

Activation of hepatic stellate cells is the central event in hepatic fibrosis. These perisinusoidal cells orchestrate an array of changes including degradation of the normal ECM of liver ...

The HepaStem cells have immunomodulatory properties, similar to other MSCs, and act on the hepatic stellate cells that drive hepatic fibrosis. These immunomodulatory, antifibrotic, and liver ...

A recent review published in eGastroenterology discusses recent advancements in understanding alcohol-associated liver ...

Chronic liver damage can lead to hepatitis, which causes fibrosis of the liver. This buildup of collagen and other fibrous ...

A newly published review in eGastroenterology compiles recent research on alcohol-associated liver disease (ALD), offering an ...

Chronic liver damage can lead to hepatitis, which causes fibrosis of the liver. This buildup of collagen and other fibrous ...

A research team investigates how mushroom extract AHCC could prevent liver fibrosis by targeting key mechanisms, with ...

When TGF-β is converted from its biologically inactive form (LTGF-β) to its active form (TGF-β), it promotes fibrosis by activating hepatic stellate cells (HSCs). These cells transform into ...

A study in mice indicates that a shiitake extract may help suppress liver fibrosis through two different pathways.