HMGB1是一种宿主源性蛋白，通过作用于TLR4引发炎症反应，与多种炎症性疾病的发病机制相关。本研究设计的非复制性AdV载体，可在LPS和流感诱导下产生HMGB1 Box A，有效减轻巨噬细胞中的炎症 ...
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