This condition most commonly affects the big toe and knee joints. Gout symptoms come and go. Periods of increased symptoms ...

During an acute attack of gout, inflammatory mediators are released and vascular adhesion and chemotaxis of leukocytes to the inflamed joint is enhanced. 7 However, for this to have an impact on ...

What is gout Gout is a painful type of arthritis, or inflammation of joints, particularly in the big toe and knee joints. It happens as a result of hyperuricemia, or too much uric acid in the blood.

Gout attacks usually happen in a single joint, like your big toe, or your knee. Within hours, the pain and swelling can become intense. Pain relievers and anti-inflammatories are usually ...