The present study quantifies the impact of the presence of tophi and frequency of acute gout attacks on health-related quality of life (HRQOL), productivity, and healthcare resource utilization.

Gout patients frequently have a number of comorbidities, including obesity, hypertension, high serum lipid and cholesterol levels, kidney disease, diabetes, and cardiovascular disease. [2,7,19 ...

A typical attack begins in the big toe, but other areas that can be affected include the foot, ankle, knee ... forming swellings known as tophi. Chronic gout can cause joint deformities over ...