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生物谷
1 个月
PNAS:科学家揭示特殊蛋白G3BP1与人类肌萎缩性侧所硬化症发生之间的 ...
富含精氨酸的C9orf72 DPRs会加重G3BP1液-液相分离 这些无膜细胞器的一个典型例子就是应激颗粒(stress granules),即细胞在压力状态下所形成的临时结构 ...
Baylor College of Medicine
3 个月
Richard Lloyd Lab
Cytoplasmic RNA granules ((Stress Granules (SG) and P-bodies) function in translation regulation by sequestering translationally-silenced mRNAs but also play prominent roles in the integrated stress ...
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