富含精氨酸的C9orf72 DPRs会加重G3BP1液-液相分离 这些无膜细胞器的一个典型例子就是应激颗粒(stress granules),即细胞在压力状态下所形成的临时结构 ...
Cytoplasmic RNA granules ((Stress Granules (SG) and P-bodies) function in translation regulation by sequestering translationally-silenced mRNAs but also play prominent roles in the integrated stress ...