conventional T-cell differentiation processes that use stromal or feeder cells carry a risk of pathogen contamination, may result in unstable production, and involve additional costs associated ...

In terms of automation, this results in the demand for particularly gentle handling, including maintenance of a feeder cell layer during medium change. Adding to the challenge is the fact that ...

with an emphasis on ex vivo expansion and engineering of NK cells to improve number and function for adoptive immunotherapy. Our K562-based feeder cell method results in consistent, robust expansion ...