Aberrant synapse development can have pathological consequences for circuit function as demonstrated by the manifestation of devastating neurological impairments, including epilepsy and autism ...

The ultimate effect of a signal from one neuron on the next neuron depends on the function of the synapse, which is based on the type of neurotransmitter released. Excitatory synapses send signals ...

Complementary, inhibitory synapses account for the long-lasting stability of excitatory synaptic modifications, providing the ...

They conclude that sleep plays a major role in preserving synapse diversity. More information: Dimitra Koukaroudi et al, Sleep maintains excitatory synapse diversity in the cortex and hippocampus ...

An electrical impulse cannot directly cross the gap so a different mechanism has to be used. Between impulses the transmitter molecules are rapidly removed from the synaptic cleft to prevent ...