The extracellular matrix (ECM) is a dynamic bioactive acellular environment, but its critical role in driving solid tumor development, immune-cell exclusion and therapy resistance is typically ...
Our group has explored the regeneration of soft biological tissues through cell-extracellular matrix interactions, with a focus on collagen-rich environments and fibrosis. We have developed a new ...
The ECM components in fibrotic liver are similar regardless of the underlying cause. Activation of hepatic stellate cells is the central event in hepatic fibrosis. These perisinusoidal cells ...