Now, researchers led by MIT Institute Professor Ann Graybiel have found surprising patterns of dopamine signaling that suggest neuroscientists may need to refine their model of how reinforcement ...

Drugs of abuse mimic these effects, and hence, overexcite our brain’s natural reward system. Therefore, tempering drug-induced amplification of dopamine signaling is one approach to reduce the ...

Dopamine neurons therefore seem to be sensitive and flexible detectors of errors in reward prediction, signaling not that an appetitive outcome has occurred but that this outcome is different than ...

Did you know the attention, memory, and motivation challenges associated with ADHD are rooted in biology? Learn how the brain ...

If our relationship with dopamine goes both ways, meaning our behaviors affect dopamine signaling and dopamine shapes how we feel, that opens the door to optimization. If dopamine responds to what ...

Researchers have uncovered how neurotransmitters in the brain respond to the emotional content of language, shedding light on the intersection of emotion, cognition, and communication.

Background: It has been suggested that dopamine dysfunction may play a role in bipolar disorder (BD). An indirect approach to examine this issue was developed, focusing on associations between ...

CINs are critical gatekeepers in the brain's striatum, influencing reward-driven learning and motivation by modulating dopamine signaling. "Dopamine neurons drive the brain's reward system ...

Tobacco and coffee contain bioactive compounds that may reduce Parkinson's disease risk by targeting key pathways such as MAO ...