Diastolic dysfunction increasingly is recognized as an important cause of congestive heart failure (CHF). In this study, Mayo Clinic researchers surveyed a random sample of 2042 adults (age ...

Objective: Because a pseudonormal pattern of ventricular filling has never been considered in studies that reported a prevalence of left ventricular diastolic dysfunction (LVDD) between 20 and 40% ...

SRD-002 is under clinical development by Sardocor and currently in Phase II for Diastolic Heart Failure (HFpEF).

HS-135 is under clinical development by 35Pharma and currently in Phase I for Diastolic Heart Failure (HFpEF).

and objective evidence of left ventricular diastolic dysfunction or raised left ventricular filling pressures. In these patients, the ruling out of potential mimickers such as respiratory disease ...

Diastolic dysfunction occurs when the left ventricular myocardium is non-compliant and not able to accept blood return in a normal fashion from the left atrium. This can be a normal physiologic ...

In systolic heart failure, the heart's left lower chamber doesn't contract well, which reduces its force for pumping blood.

Heart failure is a syndrome, not a specific disease, and occurs as a final common pathway in multiple disease states. The section presents a review of diastolic congestive heart failure ...

Persistent smoking from age 10 through 24 years is associated with increased odds of premature cardiac and structural injury.

2024.101284, discusses the effect of long-term administration of green tea catechins on aging-related cardiac diastolic dysfunction and decline of troponin I. Aging is an independent risk factor ...

The test of tirzepatide, brand named Zepbound, included 731 patients with diastolic heart failure and obesity who were followed for two years. "This class of drugs continue to show benefits far ...