Do they have any relation with binding affinity? How do we search for new instances of a motif in this sea of DNA? Sequence motifs are short, recurring patterns in DNA that are presumed to have a ...

Computational pipeline SPICE systematically screens and predicts novel protein-protein binding complexes including the previously unrecognized global association and functional cooperation between ...

New research adds to our understanding of the function of the human genome. An international team of researchers has made ...

Indeed, for NF-κB and NFAT, the DNA-binding domain is comprised of two Ig-fold regions; the N-terminal Ig-motif is responsible for sequence-specific DNA binding and the linker region that ...

An international team of researchers has taken an important step toward understanding how gene expression is controlled ...

The centromere of chromosomes plays a crucial role in cell division. Using the model plant Arabidopsis thaliana, an ...

Thus, we have the structure of a genuine catalytic intermediate. Within the NTase domain is an adenylate binding pocket composed of the six peptide motifs (I, Ia, III, IIIa, IV, and V) that define the ...

The centromere of chromosomes plays a crucial role in cell division. Using the model plant Arabidopsis thaliana, an international team of researchers led by the Leibniz Institute IPK has investigated ...

DNA’s iconic double helix has long been ... Using a specially developed antibody capable of identifying and binding to i-motifs, researchers pinpointed their locations in three distinct human ...

The centromere of chromosomes plays a crucial role in cell division. Using the model plant Arabidopsis thaliana, an international team of researchers has investigated how two crucial proteins -- KNL2 ...