Cells use repair systems to fix this damage, with specialized proteins locating and binding to the damaged regions. Zooming in on individual cells The body has various mechanisms to repair DNA ...

Michael E. Cheetham works at UCL Institute of Ophthalmology and NIHR Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, 11-43 Bath ...

Advance in stem cell therapy: New technique for manipulating stem cells opens door to novel treatments Aug 13, 2024 Scientists identify how a biological pathway leads stem cells to die or regenerate ...

By inhibiting the DNA polymerases, BKC enhances the endogenous RS in cancer cells, leading to increased DNA damage. IBC specifically inhibits CHK2 to prevent DNA repair. The combined use of BKC and ...

These could include strategies to counteract oxidative stress, enhance DNA repair or even remove damaged cells before they cause harm," Skowronska-Krawczyk said. "We plan to investigate which cell ...

In old cells with enlarged nucleolus, however, DNA repair is inaccurate leading to ... plan to study nucleolar effects on aging in human stem cells. Stem cells are special because they have ...

This triple-layered technique allowed the researchers to simultaneously capture the location of DNA, RNA and specific proteins in 3D space within individual mouse embryonic stem cells. With that ...

Lorenz Studer investigates human stem cells as tools to understand normal and pathological development in the nervous system and to develop cell-based therapies. We spoke with him in 2008. My interest ...

If cells are removed from the embryo they will differentiate into any cell type. These are called embryonic stem cells. Some stem cells remain in the bodies of adults as adult stem cells.

Hallmarks of aging, such as telomere attrition, genomic instability, and epigenetic changes, contribute to stem cell dysfunction. Furthermore, alterations in deoxyribonucleic acid (DNA ...